Chong Kun Dang WONDERTOX has proven for its efficacy and safety regarding wrinkle improvement between the eyes.
There was no statistically significant difference regarding abnormality on local areas, local or whole abnormalities other than injection area between the two groups. Both formulations were relatively tolerable and safe.
1. Efficacy evaluation Primary efficacy evaluation variable - wrinkle improvement between the eyes when frowning at week 4 compared to base Secondary efficacy evaluation variable - wrinkle improvement between the eyes in general and when frowning at week 16, satisfaction level of subjects, etc.
2. Safety evaluation Vital signs/ lab test/ side effect / antibody formation test, etc.